As the Generation Ⅲ Nuclear Power Plants,HPR1000 not only meets the requirements of domestic nuclear safety codes and standards, but also international standards,such as IAEA SSG-30. In fact,HPR1000 is to be faced more safety reviews when exports abroad. Safety classification of structures,systems and components in HPR1000 is also an important area when safety reviewed. A new methodology of safety classification based on ANSI/ANS 58.14 is to be investigated and developed with some experiences considered. As a result,safety classification of HPR1000 obeying to ANSI/ANS 58.14 is basically feasibility,without essential improvements.