Orthogonal test method and simulation analysis are combined organically for the purposes of reducing the work of simulation experiment in single-stage reluctance coil launcher simulation. A small number of combinations with a balanced representation of all experiments can be used in orthogonal ex- periment. Orthogonal experiments are used to design driving coil parameter optimization simulation ex- periment. A representative group of 9 groups was selected from all 27 groups to perform finite element analysis. According to the simulation results, experimenting the optimal parameters. The results show that orthogonal experiments can be applied to the simulation of single-stage reluctance coil launcher. The simulation results provide references for the future single-stage reluctance coil launcher, and also provide a new train of thought for the simulation of multi-stage reluctance coil launcher.